The Complete First-Year Puppy Vaccination Schedule: Weeks 6 to 16
Why do puppies need vaccines every 3 to 4 weeks? Understand maternal antibody interference, core shots like Parvo and Distemper, and when it is safe to socialize.
1. The 6-8 Week Window
Maternal antibodies protect newborns but diminish by 6-8 weeks. The first DHPP (Distemper, Hepatitis, Parvovirus, Parainfluenza) shot begins stimulating your puppy's own immune defenses.
2. The 16-Week Completion
Rabies is legally required between 12-16 weeks. A final DHPP booster at 16 weeks ensures complete protective immunity before park visits.